The health effects associated with cadmium exposure depend on the way people are exposed to cadmium, how much has entered the person’s body, how long the person has been exposed for and how the person’s body responds to the exposure. For chronic cadmium exposure, effects occur mainly on the kidneys, lungs, and bones. Cadmium exerts toxic effects on the kidney, the skeletal system and the respiratory system and is classified as a human carcinogen. This review provides an update on cad-mium exposure levels and the potential adverse health effects they may elicit in adult popu-lations. Cadmium exerts toxic effects on the kidney, the skeletal system and the respiratory system and is classified as a human carcinogen.1–4 It is generally present in the environment at low levels; however, human activity has greatly increased levels in environmental media relevant Cadmium is found in cadmium fumes (CdO) and cadmium compounds. Although at low levels, chronic cadmium exposure may induce renal dysfunction. Occupational Safety & Health Administration, Occupational Safety and Health Administration, OSHA Brief - Medical Evaluation of Renal Effects of Cadmium Exposures, Worker Notification Program -Cadmium Recovery Workers (Cadmium), Integrated Risk Information System (IRIS), Safety and Health Topics Page on Carcinogens, Severe Storm and Flood Recovery Assistance. International Agency for Research on Cancer (IARC). 341 0 obj <>stream Elevated blood pressure has not been observed as a result of excessive exposures to cadmium in Japan or the workplace. Author information: (1)Department of Environmental Epidemiology, Institute for Environmental Health and Related Product Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, China. endstream endobj 297 0 obj <>/Metadata 14 0 R/OCProperties<>/OCGs[318 0 R]>>/PageLabels 292 0 R/PageLayout/OneColumn/Pages 294 0 R/PieceInfo<>>>/StructTreeRoot 46 0 R/Type/Catalog>> endobj 298 0 obj <>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageC/ImageI]/Properties<>/XObject<>>>/Rotate 0/StructParents 0/Tabs/S/Type/Page>> endobj 299 0 obj <>stream %%EOF �@�5�$�1012nq�G�g�� 317 0 obj <>/Filter/FlateDecode/ID[<5504554CA889494F8E42EC6A45DA6697>]/Index[296 46]/Info 295 0 R/Length 97/Prev 57482/Root 297 0 R/Size 342/Type/XRef/W[1 2 1]>>stream h�bbd``b`f��@���`-�=[@� �� n/�X�n Iȁ����J1H$�� 3. Health Effects. It is generally present in the environment at low levels; however, human activity has greatly increased levels in environmental media relevant to population exposure. Exposure to cadmium primarily occurs through the ingestion of contaminated food and water and, to a significant extent, through inhalation and cigarette smoking. Chronic exposure (low level over an extended period of time) can result in kidney, bone and lung disease. Health effects of cadmium exposure - a review of the literature and a risk estimate Studies on experimental animals have indicated that a single high dose of cadmium can give rise to necrosis of the testicles. Human beings get exposed to cadmium through the foods they take and in the places they live or work. For additional information regarding carcinogens, see OSHA's. Exposure routes in children are mainly via food, environmental tobacco smoke and house dust. Occupational exposure to cadmium can lead to a variety of adverse health effects including cancer. It is a highly toxic carcinogenic that is harmful to most of the body’s systems, especially to the lungs, bones, and kidneys. Cadmium exposure and accumulation in the body start at young age. Cadmium exerts toxic effects on the kidneys as well as the skeletal and respiratory systems. Who is exposed to cadmium? The level of exposure depends upon the dose, duration, and work being … human health effects from cadmium exposure: comparison between persons living in cadmium-contaminated and non-contaminated areas in northwestern thailand. 0 HUMAN EXPOSURES AND HEALTH EFFECTS Non-occupational exposure occurs mainly from active and passive inhalation of tobacco smoke and from consumption of contaminated food and water. A very intense exposure may cause hemorrhaging of the digestive tract and severe damage to the liver, kidneys and heart, resulting in death. There is no safe margin of cadmium exposure and the need to lower human exposure is desperate. Exposure routes in children are mainly via food, environmental tobacco smoke and house dust. This leaflet tells you about the possible health hazards of different forms of cadmium, the preventative measures your employer needs to apply and the precautions you should take. For a comprehensive discussion of cadmium's health effects, see OSHA Preambles to Final Rules – Cadmium. Symptoms may resolve after a week if there is no respiratory damage. Excretion from the body is limited. We focus first on key issues under-pinning health risk assessment of low-level Occupational exposure to cadmium can lead to a variety of adverse health effects including cancer. The critical health effect of cadmium is on the kidneys where it damages the blood filtration system of the kidneys, which results in proteins being excreted in urine. Cadmium and its compounds are highly toxic and exposure to this metal is known to cause cancer and targets the body's cardiovascular, renal, gastrointestinal, neurological, reproductive, and respiratory systems. 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